Yigong Shi (Chinese: 施一公) is a researcher in the field of protein X-ray crystallography.
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Dr. Shi, who received PhD in Biophysics from Johns Hopkins University in 1995, has determined the crystal structure of several critical apoptotic proteins, including apaf-1, DIAP1, and the BIR3 domain of XIAP. He was the Warner-Lambert/Parke-Davis Professor in the department of Molecular Biology at Princeton University. In June 2008, he was selected as a Howard Hughes Medical Institute investigator.[1] However, he rejected the award upon resigning his position at Princeton University in order to pursue his career at Tsinghua University, Beijing, becoming the dean of life sciences there.[2] In 2003, he was appointed a Chair Professor of Tsinghua's Department of Biological Sciences and Biotechnology. He was appointed Vice Director of Tsinghua's Institute of Biomedicine and Vice Dean of Tsinghua's Department of Biological Sciences and Biotechnology in 2007. He was appointed Dean of Tsinghua's School of Life Sciences (replacing the Department of Biological Sciences and Biotechnology) in 2009.